Deep autoencoder as an interpretable tool for Raman spectroscopy investigation of chemical and extracellular vesicle mixtures

Mohammadrahim Kazemzadeh, Miguel Martinez-Calderon, Robert Otupiri, Anastasiia Artuyants, MoiMoi Lowe, Xia Ning, Eduardo Reategui, Zachary D. Schultz, Weiliang Xu, Cherie Blenkiron, Lawrence W. Chamley, Neil G. R. Broderick, and Colin L. Hisey

Biomedical Optics Express, 2024

Placental extracellular vesicles from early-onset but not late-onset preeclampsia induce a pro-vasoconstrictive and anti-vasodilatory state in resistance arteries

Sien Yee Lau, Katie Groom, Colin L. Hisey, Qi Chen, Carolyn Barrett, Larry Chamley

BioRxiv, 2024 (preprint)

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

Joshua A. Welsh, Deborah C. I. Goberdhan, Lorraine O’Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A. P. Driedonks, Uta Erdbrügger, Juan M. Falcon-Perez, Qing-Ling Fu, Andrew F. Hill, Metka Lenassi, Sai Kiang Lim, Mỹ G. Mahoney, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana C. Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich, Reem Bagabas, Paolo Bergese, Esther M. Bridges, Marco Brucale, Dylan Burger, Randy P. Carney, Emanuele Cocucci, Rossella Crescitelli, Edveena Hanser, Adrian L. Harris, Norman J. Haughey, An Hendrix, Alexander R. Ivanov, Tijana Jovanovic-Talisman, Nicole A. Kruh-Garcia, Vroniqa Ku’ulei-Lyn Faustino, Diego Kyburz, Cecilia Lässer, Kathleen M. Lennon, Jan Lötvall, Adam L. Maddox, Elena S. Martens-Uzunova, Rachel R. Mizenko, Lauren A. Newman, Andrea Ridolfi, Eva Rohde, Tatu Rojalin, Andrew Rowland, Andras Saftics, Ursula S. Sandau, Julie A. Saugstad, Faezeh Shekari, Simon Swift, Dmitry Ter-Ovanesyan, Juan P. Tosar, Zivile Useckaite, Francesco Valle, Zoltan Varga, Edwin van der Pol, Martijn J. C. van Herwijnen, Marca H. M. Wauben, Ann M. Wehman, Sarah Williams, Andrea Zendrini, Alan J. Zimmerman, MISEV Consortium, Clotilde Théry, Kenneth W. Witwer …

Journal of Extracellular Vesicles, 2024

Limiting Brownian Motion to Enhance Immunogold Phenotyping and Superimpose Optical and Non-Optical Single-EP Analyses

Kim Truc Nguyen, Xilal Y Rima, Colin L. Hisey, Jacob Doon-Ralls, Chiranth K Nagaraj, Eduardo Reátegui

bioRxiv, 2024 (preprint)

Engineering a tunable micropattern-array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ

Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Luong T. H. Nguyen, Kristin Huntoon, Yifan Ma, Paola Loreto Palacio, Kim Truc Nguyen, Karunya Albert, Minh-Dao Duong-Thi, Nicole Walters, Kwang Joo Kwak, Min Jin Yoon, Hong Li, Jacob Doon-Ralls, Colin L. Hisey, Daeyong Lee, Yifan Wang, Jonghoon Ha, Kelsey Scherler, Shannon Fallen, Inyoul Lee, Andre F. Palmer, Wen Jiang, Setty M. Magaña, Kai Wang, Betty Y. S. Kim, L. James Lee, Eduardo Reátegui

Journal of Extracellular Vesicles, 2023

Placental Extracellular Vesicles Can Be Loaded with Plasmid DNA

Matthew Kang, Colin L. Hisey, Bridget Tsai, Yohanes Nursalim, Cherie Blenkiron, Lawrence W. Chamley

Molecular Pharmaceutics, 2023

Production of extracellular vesicles from equine embryo-derived mesenchymal stromal cells

Weilin Hou, Tanvi Damani, Kathleen Seddon, Matthew Kang, Yi Ge, David Hanlon, Fiona Hollinshead, Colin L. Hisey, Lawrence W Chamley

Reproduction, 2023

Cascaded Deep Convolutional Neural Networks as Improved Methods of Preprocessing Raman Spectroscopy Data

Mohammadrahim Kazemzadeh, Miguel Martinez-Calderón, Weiliang Xu, Lawrence W. Chamley, Colin L. Hisey, Neil G. R. Broderick

Analytical Chemistry, 2023

Investigating the consistency of extracellular vesicle production from breast cancer subtypes using CELLine adherent bioreactors

Colin L. Hisey, Anastasiia Artuyants, George Guo, Vanessa Chang, Gabrielle Reshef, Martin Middleditch, Bincy Jacob, Lawrence W. Chamley, Cherie Blenkiron

Journal of Extracellular Biology, 2022

Conducting Polymer-Coated Carbon Cloth Captures and Releases Extracellular Vesicles by a Rapid and Controlled Redox Process

Jesna Ashraf, Alireza Akbarinejad, Colin L. Hisey, Devon T. Bryant, Julie Wang, Bicheng Zhu, Clive W. Evans, David E. Williams, Lawrence W. Chamley, David Barker, Lisa I. Pilkington, Jadranka Travas-Sejdic

ACS Applied Materials & Interfaces, 2022

Classification of Preeclamptic Placental Extracellular Vesicles Using Femtosecond Laser Fabricated Nanoplasmonic Sensors

Mohammadrahim Kazemzadeh, Miguel Martinez-Calderón, Song Y. Paek, MoiMoi Lowe, Claude Aguergaray, Weiliang Xu, Lawrence W. Chamley, Neil G. R. Broderick, Colin L. Hisey

ACS Sensors, 2022

A Novel Electrochemically Switchable Conductive Polymer Interface for Controlled Capture and Release of Chemical and Biological Entities

Alireza Akbarinejad, Colin L. Hisey, Miguel Martinez-Calderón, Jeffery Low, Devon T. Bryant, Bicheng Zhu, Diane Brewster, Eddie Wai Chi Chan, Jesna Ashraf, Ziyao Wan, Anastasiia Artuyants, Cherie Blenkiron, Larry Chamley, David Barker, David E. Williams, Clive W. Evans, Lisa I. Pilkington, Jadranka Travas-Sejdic

Advanced Materials Interfaces, 2022

Deep convolutional neural networks as a unified solution for Raman spectroscopy-based classification in biomedical applications

Mohammadrahim Kazemzadeh, Colin L. Hisey, Kamran Zargar-Shoshtari, Weiliang Xu, Neil G.R. Broderick

Optics Communications, 2022

Deletion of Grin1 in mouse megakaryocytes reveals NMDA receptor role in platelet function and proplatelet formation

James I. Hearn, Taryn N. Green, Colin L. Hisey, Markus Bender, Emma C. Josefsson, Nicholas Knowlton, Juliane Baumann, Raewyn C. Poulsen, Stefan K. Bohlander, Maggie L. Kalev-Zylinska

Blood, 2022

Label-Free Classification of Bacterial Extracellular Vesicles by Combining Nanoplasmonic Sensors With Machine Learning

Mohammadrahim Kazemzadeh, Colin L. Hisey, Priscila Dauros-Singorenko, Simon Swift, Kamran Zargar-Shoshtari, Weiliang Xu

IEEE Sensors, 2022

Production of Extracellular Vesicles Using a CELLine Adherent Bioreactor Flask

Anastasiia Artuyants, Vanessa Chang, Gabrielle Reshef, Cherie Blenkiron, Lawrence W. Chamley, Euphemia Leung, Colin L. Hisey

Bioreactors in Stem Cell Biology – Methods in Molecular Biology, 2021

Space curvature-inspired nanoplasmonic sensor for breast cancer extracellular vesicle fingerprinting and machine learning classification

Mohammadrahim Kazemzadeh, Colin L. Hisey, Anastasiia Artuyants, Cherie Blenkiron, Lawrence W. Chamley, Kamran Zargar-Shoshtari, Weiliang Xu, and Neil G. R. Broderick

Biomedical Optics Express, 2021

Micropatterned growth surface topography affects extracellular vesicle production

Colin L. Hisey, James I. Hearn, Derek J. Hansford, Cherie Blenkiron, Lawrence W. Chamley

Colloids and Surfaces B: Biointerfaces, 2021

Novel Electrochemically Switchable, Flexible, Microporous Cloth that Selectively Captures, Releases, and Concentrates Intact Extracellular Vesicles

Alireza Akbarinejad, Colin L. Hisey, Diane Brewster, Jesna Ashraf, Vanessa Chang, Saman Sabet, Yohanes Nursalim, Valentina Lucarelli, Cherie Blenkiron, Larry Chamley, David Barker, David E. Williams, Clive W. Evans, Jadranka Travas-Sejdic

ACS Applied Materials & Interfaces, 2020

A versatile cancer cell trapping and 1D migration assay in a microfluidic device

Colin L. Hisey, Oihane Mitxelena-Iribarren, Miguel Martínez-Calderón, Jaymeson B. Gordon, Santiago M. Olaizola, Ainara Benavente-Babace, Maite Mujika, Sergio Arana, Derek J. Hansford

Biomicrofluidics, 2019

A Microfluidic Chip Enables Isolation of Exosomes and Establishment of Their Protein Profiles and Associated Signaling Pathways in Ovarian Cancer

Kalpana Deepa Priya Dorayappan, Miranda L. Gardner, Colin L. Hisey, Roman A. Zingarelli, Brentley Q. Smith, Michelle D.S. Lightfoot, Rajan Gogna, Meghan M. Flannery, John Hays, Derek J. Hansford, Michael A. Freitas, Lianbo Yu, David E. Cohn, Karuppaiyah Selvendiran

Cancer Research, 2019

Microfluidic affinity separation chip for selective capture and release of label-free ovarian cancer exosomes

Colin L. Hisey, Kalpana Deepa Priya Dorayappan, David E. Cohn, Karuppaiyah Selvendiran, Derek J. Hansford

Lab on a Chip, 2018

Effectiveness of nanoencapsulated methotrexate against osteosarcoma cells: in vitro cytotoxicity under dynamic conditions

O. Mitxelena-Iribarren, Colin L. Hisey, M. Errazquin-Irigoyen, Y. González-Fernández, E. Imbuluzqueta, M. Mujika, M. J. Blanco-Prieto & S. Arana

Biomedical Microdevices, 2017

The effect of single wall carbon nanotube metallicity on genomic DNA-mediated chirality enrichment

Steve S. Kim, Colin L. Hisey, Zhifeng Kuang, Donald A. Comfort, Barry L. Farmer, Rajesh R. Naik

Nanoscale, 2013